您的位置 : 2012年获得厦门大学植物学博士学位，先后在杭州师范大学、美国杜克大学从事科研工作。主要从事植物细胞钙离子(Ca2+)及活性氧/氮/硫 (ROS, RNS, RSS)等信号分子在响应逆境胁迫中的作用机制研究。共发表SCI论文31篇，总引用数1300余次，H因子17，4篇论文被Web of Science评为前1%高被引论文。
近期工作主要集中于利用植物细胞钙信号成像技术来寻找植物对过氧化氢(H2O2，活性氧)胁迫的感受机制。2020年2月，以第一作者在《自然》（Nature）上发表研究论文，首次报道了植物细胞表面的过氧化氢受体，为进一步解析植物生物、非生物胁迫应答机制提供了全新的途径，在高抗作物育种中应用潜力广阔(Wu et al., Nature, 2020 578, 577-581)。此外还作为主要参与人发现植物可通过质膜鞘脂GIPC来感受盐胁迫(Jiang et al., Nature, 2019, 572,341-346)；及植物辅助性免疫受体在抗病过程中作为新型钙离子通道发挥功能的作用机制(Jacob et al., Science, 2021)。
主要代表作：
1. Wu, F.H., Chi, Y.; Jiang, Z. H.; Xu, Y. Y.; Xie, L.; Huang, F. F.; Wan, D.; Ni, J.; Yuan, F.; Wu, X. M.; Zhang, Y. Y.; Wang, L.; Ye, R.; Byeon, B.; Wang, W. H.; Zhang, S.; Sima, M.; Chen, S. P.; Zhu, M. H.; Pei, J. S.; Johnson, D. M.; Zhu, S.; Cao, X. Q.; Pei, C.; Zai, Z. J.; Liu, Y. H.; Liu, T. Y.; Swift, G. B.; Zhang, W. G.; Yu, M.; Hu, Z. L.; Siedow, J. N.; Chen, X.; Pei, Z. M.#. (2020). Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis. Nature, 578(7796), 577–581.
(引用298次，Web of Science高被引/热点论文；Nature同期配发导读文章；Faculty 1000 植物学领域推荐指数前0.02%，)
2. Jacob, P.*, Kim, N. H.*, Wu, F., El Kasmr, F., Chi, Y., Walton, W. G., Furzer, O. J., Lietzan, A. D., Sunil, S., Kempthorn, K., Redinbo, M. R., Pei, Z.-M.#, Wan, L.#, & Dangl, J. L.# (2021). Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels. Science, 373(6553), 420-425.
(引用106次，Web of Science高被引/热点论文)
3. Jiang, Z.H., Zhou, X.P., Tao, M., Yuan, F., Liu, L.L., Wu, F.H., Wu, X.M., Xiang, Y., Niu, Y., Liu, F., et al. (2019). Plant cell-surface GIPC sphingolipids sense salt to trigger Ca2+ influx. Nature 572(7769), 341-346.
(引用312次，Web of Science高被引论文；Nature同期配发导读文章)
4. Chi, Y., Wang, C., Wang, M., Wan, D., Huang, F., Jiang, Z., Crawford, B. M., Vo-Dinh, T., Yuan, F., Wu, F.H.#, & Pei, Z.-M.# (2021). Flg22-induced Ca2+ increases undergo desensitization and resensitization. Plant, Cell & Environment. 44(12), 3793–3805. （共同通讯作者）
5. Li, X., Ou, M., Li, L., Li, Y., Feng, Y., Huang, X., Baluška, F., Shabala, S., Yu, M., Shi, W.#, Wu, F.H.#, 2023. The wall-associated kinase gene family in pea (Pisum sativum) and its function in response to B-deficiency and Al toxicity. Journal of Plant Physiology 154045. （共同通讯作者）
6. Wu X*, Wu FH*, Wang X*, Wang L, Siedow JN, Zhang W, Pei ZM. (2014) Molecular evolutionary and structural analysis of the cytosolic DNA sensor cGAS and STING. Nucleic Acids Res. 42(13):8243-8257. (共同第一作者)
7. Chen J.*, Wu F.H.*, Wang W.H., Zheng C.J., Lin G.H., Dong X.J., He J.X., Pei Z.M. and Zheng H.L. (2011). Hydrogen sulphide enhances photosynthesis through promoting chloroplast biogenesis, photosynthetic enzyme expression, and thiol redox modification in Spinacia oleracea seedlings. J Exp Bot., 62(13): 4481-4493.(共同第一作者；Web of Science高被引论文)
8. Wu, X.*, Wu, FH.*, Wu, Q., Zhang, S., Chen, S., and Sima, M. (2017). Phylogenetic and Molecular Evolutionary Analysis of Mitophagy Receptors under Hypoxic Conditions. Frontiers in Physiology 8. DOI:10.3389/fphys.2017.00539 (共同第一作者)
9. Wu, F.H., Chen, J., Liu, T.W., Li, Z.J., Chen, J., Chen, L., Guan, S.H., Li, T.Y., Dong, X.J., Patton, J., et al. (2013). Differential responses of Abies fabri and Rhododendron calophytum at two sites with contrasting pollution deposition and available calcium in southwestern China. Plant Ecol 214, 557-569.
10. Chen L.*, Wu F.H.*, Liu T.W., Chen J., Li Z.J., Pei Z.M. and Zheng H.L. (2010). Soil acidity reconstruction based on tree ring information of a dominant species Abies fabri in the subalpine forest ecosystems in southwest China. Environ Pollut, 158(10): 3219-3224.(共同第一作者)
11. Tao, L., Xiao, X., Huang, Q., Zhu, H., Feng, Y., Li, Y., Li, X., Guo, Z., Liu, J., Wu, F., Pirayesh, N., Mahmud, S., Shen, R. F., Shabala, S., Baluška, F., Shi, L., & Yu, M. (2023). Boron supply restores aluminum-blocked auxin transport by the modulation of PIN2 trafficking in the root apical transition zone. The Plant Journal, 114(1), 176–192.
12. Huang, F., Wu, F., Yu, M., and Shabala, S. (2022). Nucleotide-binding leucine-rich repeat proteins: a missing link in controlling cell fate and plant adaptation to hostile environment? J.Exp.Bot. 73, 631–635.
13. Chen, X., Humphreys, J.L., Ru, Y., He, Y., Wu, F., Mai, J., Li, M., Li, Y., Shabala, S., Yu, M., et al. (2022). Jasmonate signaling and remodeling of cell wall metabolism induced by boron deficiency in pea shoots. Environmental and Experimental Botany 201, 104947.
14. Chen, J., Shen, Z.J., Lu, W.Z., Liu, X., Wu, F.H., Gao, G.F., Liu, Y.L., Wu, C.S., Yan, C.L., Fan, H.Q., et al. (2017). Leaf miner-induced morphological, physiological and molecular changes in mangrove plant Avicennia marina (Forsk.) Vierh. Tree Physiol 37, 82–97.
15. Liu X, Wu FH, Li JX, Chen J, Wang GH, Wang WH, Hu WJ, Gao LJ, Wang ZL, Chen JH, Simon M, Zheng HL. (2016) Glutathione homeostasis and Cd tolerance in the Arabidopsis sultr1;1-sultr1;2 double mutant with limiting sulfate supply. Plant Cell Rep. 35(2):397-413.
16. Hu WJ, Wu Q, Liu X, Shen ZJ, Chen J, Liu TW, Chen J, Zhu CQ, Wu FH, Chen L, Wei J, Qiu XY, Shen GX, Zheng HL. (2016) Comparative Proteomic Analysis Reveals the Effects of Exogenous Calcium against Acid Rain Stress in Liquidambar formosana Hance Leaves. J Proteome Res. 15(1):216-28.
17. Chen J, Wu FH, Shang YT, Wang WH, Hu WJ, Simon M, Liu X, Shangguan ZP, Zheng HL. (2015) Hydrogen sulphide improves adaptation of Zea mays seedlings to iron deficiency. J Exp Bot. 66(21):6605-22.
18. Chen J, Wang WH, Wu FH, He EM, Liu X, Shangguan ZP, Zheng HL. (2015) Hydrogen sulfide enhances salt tolerance through nitric oxide-mediated maintenance of ion homeostasis in barley seedling roots. Sci Rep. doi:10.1038/srep12516.
19. Chen, J., Wang, C., Wu, F.H., Wang, W.H., Liu, T.W., Chen, J., Xiao, Q., He, B.Y., and Zheng, H.L. (2015). Variation of nitric oxide emission potential in plants: a possible link to leaf N content and net photosynthetic activity. J Plant Ecol 8, 313-320.
20. Hu WJ, Chen J, Liu TW, Wu FH, Chen J, Wang WH, Liu X, Zheng HL, (2014) Combined calcium-related genes and proteomic analysis of defense response to acid rain stress under different calcium levels in Pinus massoniana, Plant and Soil, 380(1):285-303.
21. Liu TW, Chen J, Wang WH, Simon M, Wu FH, Hu WJ, Chen J, Zheng HL, (2014) A combined proteomic and transcriptomic analysis on sulfur metabolism pathways of Arabidopsis thaliana under simulated acid rain, Plos ONE, doi:10.1371/journal. pone.0090120
22. Chen, J., Xiao, Q., Wang, C., Wang, W.H., Wu, F.H., Chen, J., He, B.Y., Zhu, Z., Ru, Q.M., Zhang, L.L., et al. (2014). Nitric oxide alleviates oxidative stress caused by salt in leaves of a mangrove species, Aegiceras corniculatum. Aquat Bot 117, 41-47
23. Hu WJ, Chen J, Liu TW, Liu X, Chen J, Wu FH, Wang WH, He JX, Xiao Q, Zheng HL. (2014) Comparative proteomic analysis on wild type and nitric oxide-overproducing mutant (nox1) of Arabidopsis thaliana. Nitric Oxide. 36:19-30.
24. Hu WJ, Chen J, Liu TW, Simon M, Wang WH, Chen J, Wu FH, Liu X, Shen ZJ, Zheng HL. (2014) Comparative proteomic analysis of differential responses of Pinus massoniana and Taxus wallichiana var. mairei to simulated acid rain. Int J Mol Sci. 15(3):4333-55. doi: 10.3390/ijms15034333.
25. Chen J, Wang WH, Wu FH, You CY, Liu TW, Dong XJ, He JX, Zheng HL, (2013) Hydrogen sulfide alleviates aluminum toxicity in barley seedlings, Plant and Soil, 362:301-318.
26. Liu TW, Niu L, Fu B, Chen J, Wu FH, Chen J, Wang WH, Hu WJ, He JX, Zheng HL. (2013) A transcriptomic study reveals differentially expressed genes and pathways respond to simulated acid rain in Arabidopsis thaliana. Genome. 56(1):49-60.
27. Chen J, Wang WH, Liu TW, Wu FH, Zheng HL. (2013) Photosynthetic and antioxidant responses of Liquidambar formosana and Schima superba seedlings to sulfuric-rich and nitric-rich simulated acid rain. Plant Physiol Biochem. 64:41-51.
28. Chen J, Wu FH, Liu TW, Chen L, Xiao Q, Dong XJ, He JX, Pei ZM, Zheng HL. (2012) Emissions of nitric oxide from 79 plant species in response to simulated nitrogen deposition. Environ Pollut. 160(1):192-200.
29. Wang W.H., Yi X.Q., Han A.D., Liu T.W., Chen J., Wu F.H., Dong X.J., He J.X., Pei Z.M. and Zheng H.L., (2012) Calcium-sensing receptor regulates stomatal closure through hydrogen peroxide and nitric oxide in response to extracellular calcium in Arabidopsis. J Exp Bot., 63(1):177-90.
30. Liu T.W., Wu F.H., Wang W.H., Chen J., Li Z.J., Dong X.J., Patton J., Pei Z.M. and Zheng H.L., 2011. Effects of calcium on seed germination, seedling growth and photosynthesis of six forest tree species under simulated acid rain. Tree Physiol, 31(4): 402-413.
31. Chen J., Wu F.H., Xiao Q., Yang Z.H., Huang S.K., Wang J.A., Wu Y.G., Dong X.J., Pei Z.M. and Zheng H.L. (2010). Diurnal variation of nitric oxide emission flux from a mangrove wetland in Zhangjiang River Estuary, China. Estuar Coast Shelfs, 90(4): 212-220.
联系方式：feihua.wu@outlook.com
